Selective reduction of allelic variants

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United States of America Patent

PATENT NO 9006198
SERIAL NO

13577622

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Abstract

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Disclosed herein are antisense compounds and methods for selectively reducing expression of an allelic variant of a huntingtin gene containing a single nucleotide polymorphism (SNP). Such methods, compounds, and composition are useful to treat, prevent, or ameliorate Huntington's Disease (HD).

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Patent Owner(s)

Patent OwnerAddress
IONIS PHARMACEUTICALS INC2855 GAZELLE CT CARLSBAD CA 92010-6670

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bennett, C Frank Carlsbad, US 412 7677
Carroll, Jeffrey Vancouver, CA 12 136
Freier, Susan M San Diego, US 526 6555
Greenlee, Sarah San Diego, US 10 144
Hayden, Michael Vancouver, CA 76 372
Swayze, Eric E Encinitas, US 355 10308
Warby, Simon Victoria, CA 7 128

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