AAV virions with decreased immunoreactivity and uses therefor

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United States of America Patent

PATENT NO 9506083
APP PUB NO 20080008690A1
SERIAL NO

11825798

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Abstract

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Methods of making and using recombinant AAV virions with decreased immunoreactivity are described. The recombinant AAV virions include mutated capsid proteins or are derived from non-primate mammalian AAV serotypes and isolates that display decreased immunoreactivity relative to AAV-2.

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Patent Owner(s)

Patent OwnerAddress
GENZYME CORPORATION450 WATER STREET CAMBRIDGE MA 02141

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Arbetman, Alejandra Elena San Francisco, US 4 101
Colosi, Peter C Alameda, US 23 402
Lochrie, Michael A Hayward, US 10 365
Surosky, Richard T Oakland, US 10 105

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