KDR AND VEGF/KDR BINDING PEPTIDES

World Intellectual Property Organization Patent

APP PUB NO WO-2006031885-A2
SERIAL NO

PCTUS2005032740

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The present invention provides, inter alia, peptides, peptide dimer, and multimeric complexes comprising at least one binding moiety for KDR or VEGF/KDR complex, which have a variety of uses wherever treating, detecting, isolating or localizing angiogenesis is advantageous. Particularly disclosed are synthetic, isolated polypeptides capable of binding KDR or VEGF/KDR complex with high affinity (e.g., having a KD < 1 µM), and dimer and multimeric constructs comprising these polypeptides.

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