SYNAPSE-SPECIFIC PROTEINS IN GLOMERULI

World Intellectual Property Organization Patent

APP PUB NO WO-2007026246-A2
SERIAL NO

PCTIB2006002764

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The present invention identifies that glomeruli express many neuron-specific and especially synapse-specific protein similarities. In particular, the present invention identifies Rab3A expression, including the expression of altered forms, as well as expression of other synapse-specific proteins including neurotransmitter receptors. The invention further identifies that modulation of the activity of these synapse-specific proteins results in modulation of podocytes.

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