NOVEL 2-AMINO-IMIDAZOLE-4-ONE COMPOUNDS AND THEIR USE IN THE MANUFACTURE OF A MEDICAMENT TO BE USED IN THE TREATMENT OF COGNITIVE IMPAIRMENT, ALZHEIMER’S DISEASE, NEURODEGENERATION AND DEMENTIA

World Intellectual Property Organization Patent

APP PUB NO WO-2007058601-A1
SERIAL NO

PCTSE2006001316

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Abstract

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This invention relates to novel compounds having the structural formula I below and to their pharmaceutically acceptable salts, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.

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Patent Owner(s)

Patent OwnerAddress
ASTRAZENECA ABSESE-151 85 SODERTALJE

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Inventor(s)

Inventor Name Address
CONGREVE MILES STUART C/O HEPTARES THERAPEUTICS LIMITED GRANTA PARK GREAT ABINGTON CAMBRIDGE CAMBRIDGESHIRE CB21 6DG CB21 6DG
MURRAY CHRISTOPHER DERBY DE24 8BJ
CHESSARI GIANNI CAMBRIDGE CAMBRIDGESHIRE CB4 0QA
PATEL SAHIL CAMBRIDGE CB4 0QA
EDWARDS PHIL KENNETH SQUARE MA 19348
ARNOLD JAMES C/O HARVARD UNIVERSITY SMITH CENTER - SUITE 727 1350 MASSACHUSETTS AVE CAMBRIDGE MA 02138 02138
ALBERT JEFFREY WILMINGTON DELAWARE 19850-5437

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