A BIODEGRADABLE MICROSPHERE COMPOSITION SUITABLE FOR THE CONTROLLED RELEASE OF GLUCOSE CONTROLLING PEPTIDE AND FORMULATION THEREOF

World Intellectual Property Organization Patent

APP PUB NO WO-2008130158-A1
SERIAL NO

PCTKR2008002216

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Abstract

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Disclosed are biodegradable microspheres, capable of releasing a glucose-regulating peptide in a controlled manner, comprising a biodegradable polymer carrier with the glucose-regulating peptide encapsulated therein, and methods for the preparation thereof. In addition to ensuring high encapsulation efficiency and high stability of the encapsulated drug, the microspheres shows neither an initial burst effect nor incomplete release and allows the zero-order release of drugs over a prolonged period of time, thus improving the therapeutic effect of the drug.

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Patent Owner(s)

Patent OwnerAddress
DONG-A PHARMACEUTICAL CO LTDKRSEOUL 130-072

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Inventor(s)

Inventor Name Address
YOO MOOHI 135-807 SEOUL
LEE SUNG HEE 37623 경상북도 포항시 북구 두호로 66 108-1502 GYEONGSANGBUK-DO 37623
KANG SOO HYUNG YONGIN-SI
KIM BYONG MOON SEOUL 135-837
KWAK HYUN HEE 04733 서울특별시 성동구 매봉길 15 101동 401호 SEOUL 04733
LEE GHUN IL #207-1004 UNAMFIRSTVILL ANHWADONGMAEUL 847 BYEONGJEOM-DONG HWASEONG-SI GYEONGGI-DO 445-779
PARK YONG MAN 16911 GYEONGGI-DO
SON MI KYUNG YONGIN-SI
YANG HI CHANG YONGIN-SI
KIM TAE HYOUNG PYEONGTAEK-SI
KIM YOON JI GWANGJU

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