INTERLEUKIN-21 RECEPTOR BINDING PROTEINS

World Intellectual Property Organization Patent

APP PUB NO WO-2009143523-A1
SERIAL NO

PCTUS2009045182

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Abstract

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The present invention provides binding proteins and antigen-binding fragments thereof that specifically bind to the human interleukin-21 receptor (IL-21R). The binding proteins can act as, e.g., antagonists of IL-21R activity, thereby modulating immune responses in general, and those mediated by IL-21R in particular. The disclosed compositions and methods may be used, e.g., in diagnosing and/or treating IL-21R-associated disorders, e.g., inflammatory disorders, autoimmune diseases, allergies, transplant rejection, cancer, and other immune system disorders.

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Patent Owner(s)

Patent OwnerAddress
WYETH CORPUSNEW JERSEY

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Inventor(s)

Inventor Name Address
VALGE-ARCHER VIIA CAMBRIDGE CB1 6GH
YOUNG DEBORAH A MELROSE MA 02176
VUGMEYSTER YULIA WINCHESTER MA 01890
GILL DAVINDER BURLINGTON MA
BLOOM LAIRD C/O PFIZER INC 610 MAIN STREET CAMBRIDGE MASSACHUSETTS 02139 02139
LOWE DAVID ROYSTON

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