METHODS OF DIAGNOSING AND TREATING FIBROSIS

World Intellectual Property Organization Patent

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May 6, 2010
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Nov 2, 2009
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Oct 31, 2008

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Abstract

The present invention is directed to methods of diagnosing and treating a fibrotic condition in a mammalian subject. These methods involve measuring the levels of trimethylation at lysine residue 27 of histone-3 and/or measuring the expression levels of EZH2 or YY-1. Agents useful for treating fibrosis or a fibrotic condition are also disclosed.

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UNIV ROCHESTER	USUSA NEW YORK

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C12Q:MEASURING OR TESTING PROCESSES INVOLVING ENZYMES O....

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Inventor Name	Address
LIN XIN	SANTA CLARA CA
GUO JIA	CHANDLER
GEORAS STEVE	ROCHESTER NY
SIME PATRICIA	PITTSFORD NY

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2010051550

METHODS OF DIAGNOSING AND TREATING FIBROSIS

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METHODS OF DIAGNOSING AND TREATING FIBROSIS

World Intellectual Property Organization Patent

PCTUS2009063016

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PCTUS2009063016

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