OLIGOMERIC COMPOUNDS AND EXCIPIENTS

World Intellectual Property Organization Patent

APP PUB NO WO-2010091301-A1
SERIAL NO

PCTUS2010023383

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Abstract

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The present invention provides method of optimizing the efficacy and potency of antisense compounds. In certain embodiments, the invention provides assays useful for determining favorable oligonucleotide characteristics and excipients for improved cellular uptake.

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Patent Owner(s)

Patent OwnerAddress
ISIS PHARMACEUTICALS INCUSCARLSBAD CA 92010

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Inventor(s)

Inventor Name Address
BENNETT C FRANK CARLSBAD CA
SWAYZE ERIC E ENCINITAS CA
SIWKOWSKI ANDREW M CARLSBAD CA 92009
GEARY RICHARD S CARLSBAD 92010

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