METHOD FOR PURIFYING BIO-ORGANIC COMPOUNDS FROM FERMENTATION BROTH CONTAINING SURFACTANTS BY TEMPERATURE-INDUCED PHASE INVERSION

World Intellectual Property Organization Patent

APP PUB NO WO-2012024186-A1
SERIAL NO

PCTUS2011047616

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Abstract

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Methods and systems for purifying bio-organic compounds are described. In certain embodiments, the methods comprise the steps of (a) providing a composition or an emulsion comprising a surfactant, host cells, an aqueous medium and a bio-organic compound produced by the host cells, wherein the solubility of the surfactant in the aqueous medium decreases with increasing temperature and wherein the temperature of the composition or emulsion is at least about 1 °C below a phase inversion temperature of the composition or emulsion; (b) raising the temperature of the composition or emulsion to at least about 1 °C above the phase inversion temperature; and (c) performing a liquid/liquid separation of the composition to provide a crude bio-organic composition or emulsion.

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Patent Owner(s)

Patent OwnerAddress
AMYRIS INCUSEMERYVILLE CA 94608

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Inventor(s)

Inventor Name Address
DORIN GLENN 155 HUMBOLT SAN RAFAEL CALIFORNIA
TABUR PINAR EMERYVILLE CA 94608

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