COMPOSITIONS AND METHODS FOR HEPARAN SULFATE AS A BIOMARKER FOR TRANSPLANT REJECTION

World Intellectual Property Organization Patent

APP PUB NO WO-2013166163-A1
SERIAL NO

PCTUS2013039086

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Abstract

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The present disclosure provides methods of identifying transplant rejection through the use of heparan sulfate as a biomarker. Method also comprise treating and/or preventing transplant rejection in a subject comprising administering to the subject a heparan sulfate inhibitor, thereby treating and/or preventing the development of immune-mediated injury following transplantation.

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Patent Owner(s)

Patent OwnerAddress
UNIV DUKEUS2812 ERWIN ROAD SUITE 406 BOX 90083 DURHAM NORTH CAROLINA 27705 27705

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Inventor(s)

Inventor Name Address
YANG YIPING CHAPEL HILL NC
BRENNAN TODD V DURHAM NC

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