IRON CHELATORS AS HIV-1 INHIBITORS

World Intellectual Property Organization Patent

APP PUB NO WO-2013169361-A1
SERIAL NO

PCTUS2013031231

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Abstract

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The present invention relates to chelator compounds for chelating metal ions. In particular, the present invention relates to (thio)semicarbazone compounds and (thio)hydrazone compounds, such as PpYeT and PpYaT, which are chelators for metal ions, including iron ions. Therapeutic use of such compounds and/ or their metal ion complexes, includes methods for treating and inhibiting HIV-1 replication, particularly in HIV-1 infected cells.

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Patent Owner(s)

Patent OwnerAddress
UNIV HOWARDUS

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Inventor(s)

Inventor Name Address
NEKHAI SERGEI WASHINGTON DISTRICT OF COLUMBIA 20059
KOVALSKYY DMYTRO BORISOVYCH SAN ANTONIO TX 78231

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