ENGINEERING THE PRODUCTION OF A CONFORMATIONAL VARIANT OF OCCIDIOFUNGIN THAT HAS ENHANCED INHIBITORY ACTIVITY AGAINST FUNGAL SPECIES

World Intellectual Property Organization Patent

APP PUB NO WO-2014085419-A1
SERIAL NO

PCTUS2013071941

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Abstract

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Occidiofungin is a cyclic nonribosomally synthesized antifungal peptide with submicromolar activity. This invention is directed to compositions enriched for particular occidiofungin diastereomers/conformers, methods of making compositions enriched for particular diastereomers/conformers and microorganisms suitable for producing enriched compositions of particular diastereomers/conformers. Methods of treating fungal infections or plants infected by fungi are also provided.

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Patent Owner(s)

Patent OwnerAddress
TEXAS A & M UNIV SYSUSTHE AMERICAN STATE OF ARKANSAS

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Inventor(s)

Inventor Name Address
SMITH JAMES LEIF COLLEGE STATION TX
GU GANYU STARKVILLE MS 39759
RAVICHANDRAN AKSHAYA COLLEGE STATION TX
LU SHEIN STARKVILLE MS 39759

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