NOVEL POLYMORPHS OF CABOZANTINIB (S)-MALATE AND CABOZANTINIB FREE BASE

World Intellectual Property Organization Patent

APP PUB NO WO-2015177758-A1
SERIAL NO

PCTIB2015053765

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Abstract

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The present disclosure provides novel crystalline forms of cabozantinib (S)-malate, designated as form-M1, M2, M3 and M4 and novel crystalline forms of cabozantinib free base, form-M1, M2 and M3 and methods of their production. The present disclosure also provides processes for the preparation of crystalline cabozantinib (S)-malate form N-1. Formula (I)

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Patent Owner(s)

Patent OwnerAddress
MYLAN LAB LTDIN

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Inventor(s)

Inventor Name Address
GORE VINAYAK HYDERABAD 500033
JETTI RAMAKOTESWARA RAO MYLAN LABORATORIES LTD PLOT NO 564/A/22 ROAD NO 92 JUBILEE HILLS HYDERABAD 500033 500033
INDUKURI ANJANEYARAJU S/O BHASKARARAJU PLOT NO 64 65 FLAT NO 303 ADROIT AVENUE NEAR JAYABHERI PARK KOMPALLY HYDERABAD 500014 500014
PUNDE DNYANDEO HYDERABAD 500033
BOHRA CHANDERSINGH HYDERABAD 500033
GADAKAR MAHESH KUMAR HYDERABAD 500033

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