ENHANCED PROTEIN EXPRESSION

World Intellectual Property Organization Patent

APP PUB NO WO-2016099917-A1
SERIAL NO

PCTUS2015063636

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Abstract

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The present invention relates in general to bacterial cells having genetic alterations that result in increased expression of a protein of interest and methods of making and using such cells. Aspects of the present invention include altered Gram positive microorganismshaving one or more a genetic alterations that reduce the expression of a gene in the sin operon, thereby resulting in the enhanced expression of one or more proteins of interest.

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Patent Owner(s)

Patent OwnerAddress
DANISCO US INCUSPALO ALTO CA

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Inventor(s)

Inventor Name Address
VAN KIMMENADE ANITA PALO ALTO CALIFORNIA 94304
SCHMIDT BRIAN F PALO ALTO CALIFORNIA 94304
BONGIORNI CRISTINA 925 PAGE MILL ROAD PALO ALTO CALIFORNIA 94304 94304
GONZALES CAGUIAT RODANTE PALO ALTO CALIFORNIA 94304
NMI FIORESI CAROL PALO ALTO CALIFORNIA 94304
ZHU CHAO CLARK NJ 07066

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