NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF

World Intellectual Property Organization Patent

APP PUB NO WO-2016134301-A2
SERIAL NO

PCTUS2016018748

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Abstract

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Described herein are neuroactive steroids of the Formula (I): (I) or a pharmaceutically acceptable salt thereof; wherein R1, R2, Ra, G, X, Y, Z, and n are as defined herein. Such compounds are envisioned, in certain embodiments, to behave as GABA modulators. Also provided are pharmaceutical compositions comprising a compound described herein and methods of use and treatment, e.g., such for inducing sedation and/or anesthesia.

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