SYK INHIBITORS

World Intellectual Property Organization Patent

Stats

Importance

Loading Importance Indicators... loading....

Abstract

See full text

The application provides methods reducing the side effects of chemotherapy and radiotherapy, including, hematopoietic toxicity, anemia, myelosuppression, pancytopenia, thrombocytopenia, neutropenia, lymphopenia, leukopenia, stomatitis and alopecia. The application provides a method for increasing the number of, neutrophil counts and platelet counts in a patient in need thereof, comprising administering an effective of an inhibitor of spleen tyrosine kinase (SYKi). The present application provides methods for treating myelosuppresive disorders by the administration of a SYKi. In certain embodiments, the myelosuppression is induced by the administration of one or more myelosuppressive agents, for example, anti-cancer drugs. The present application provides methods for treating AML/ALL in a patient with 11q23/MLL abnormalities comprising the step of administering an effective amount of a SYKi to said patient.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
GILEAD SCIENCES INCUSFOSTER CITY CA 94404

International Classification(s)

  • [Classification Symbol]
  • [Patents Count]

Inventor(s)

Inventor Name Address
ABELLA ESTEBAN M FOSTER CITY CALIFORNIA 94404
MARCONDES ANTONIO MARIO QUERIDO FOSTER CITY CALIFORNIA 94404
RAO ARATI V FOSTER CITY CALIFORNIA 94404

Cited Art Landscape

Load Citation