POLYMERS CONTAINING BETA-AMINO-ESTER (BAE) AND BETA-THIO-ESTER (BTE)

World Intellectual Property Organization Patent

APP PUB NO WO-2023108111-A2
SERIAL NO

PCTUS2022081249

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Provided herein are branched BAE/BTE -containing polymers useful as vehicles for the delivery of therapeutic agents, such as nucleic acids. The polymers form stable compositions and are suitable for the delivery of therapeutic agents via nebulization. Compositions of the disclosed polymers are capable of delivering therapeutic agents such as mRNA to lung epithelial cells.

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