TWO-PHASE DELIVERY OF PLASMA

World Intellectual Property Organization Patent

APP PUB NO WO-2024059771-A1
SERIAL NO

PCTUS2023074274

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Abstract

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The present invention relates to a spray dried plasma composition having one or more of the following characteristics: when reconstituted, largely amorphous and has no cholesterol crystals; when reconstituted, the number of large particulates is reduced; has low residual moisture; reconstitutes rapidly in under four minutes; highly stable when stored under refrigeration, at room temperature or at elevated temperatures and allows for storage for longer periods of time; when reconstituted, exhibits recovery of the most fragile of proteins, including von Willebrand's factor; when reconstituted with Sterile Water for Injection (SWFI), reconstituted plasma is at a pH that is near normal plasma pH, and does so without treatment or storage in CO2 or other pH adjustment.

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Patent Owner(s)

Patent OwnerAddress
VELICO MEDICAL INCUSBEVERLY MA

International Classification(s)

Inventor(s)

Inventor Name Address
MERRITT WILLIAM J DANVERS MA
SNYDER HERMAN E W LAFAYETTE IN
ANDREWS ROBERT R NORFOLK MA
LIU QIYONG PETER C/O TRANSCODE THERAPEUTICS INC 6 LIBERTY SQUARE #2382 BOSTON MA 02109 02109
BUCKLEY LISA A PORTLAND OR
STROHL CLAIR EMMAUS PA 18049
SOHN JIHAE 28 GROVE STREET SALEM MA 01970 01970
ORDWAY EVAN P SALEM MA
POPOVSKY MARK A SHARON MA
MEEHAN RICHARD KILDARE

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