Aromatic heterocyclic compounds and their use as anti-inflammatory agents
Regan, John R; Cirillo, Pier F; Hickey, Eugene R; Moss, Neil ; Cywin, Charles L; Pargellis, Christopher ; Gilmore, Thomas A
BOEHRINGER INGELHEIM PHARMACEUTICALS, INC.;
Attorney, Agent or Firm:
Raymond Robert P. Bottino Anthony P. Stempel Alan R.
Novel aromatic heterocyclic compounds inhibit cytokines production involved in immunoregulation and inflammation such as interleukin-1 and tumor necrosis factor production. The compounds are therefore useful in pharmaceutic compositions for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases.
Jun 27, 2000
Oct 29, 1998