Hydroxamate inhibitors of interleukin-1.beta. converting enzyme

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United States of America Patent

PATENT NO 5919790
SERIAL NO

08942605

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to compounds that are inhibitors of interleukin-1.beta. converting enzyme that have the Formula II ##STR1## This invention also relates to a method of treatment of stroke, inflammatory diseases, septic shock, reperfusion injury, Alzheimer's disease, shigellosis, and to a pharmaceutically acceptable composition that contains a compound that is an inhibitor of interleukin-1.beta. converting enzyme.

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Patent Owner(s)

  • ABBOTT GMBH & CO. KG;WARNER-LAMBERT COMPANY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Allen, Hamish John Shrewsbury, MA 7 70
Brady, Kenneth Dale Worcester, MA 7 77
Caprathe, Bradley William Livonia, MI 9 104
Galatsis, Paul Ann Arbor, MI 11 64
Gilmore, John Lodge Ann Arbor, MI 2 32
Hays, Sheryl Jeanne Ann Arbor, MI 6 46
Talanian, Robert Vincent Harvard, MA 4 63
Walker, Nigel Dossenheim, DE 12 175
Warmus, Joseph Scott Ann Arbor, MI 10 220

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