Ester and alkoxy substituted benzopyrans

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United States of America Patent

PATENT NO 5412104
SERIAL NO

08030186

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Abstract

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Compounds useful as antihypertensive agents and useful as antiviral agents against DNA-containing viruses, such as herpes group viruses, are disclosed. The compounds are represented by Formula 1.0: ##STR1## and their pharmaceutically acceptable salts and solvates. Pharmaceutical compositions containing compounds represented by Formula 1.0 are disclosed. Methods of treating a viral infection using compounds represented by Formula 1.0 are disclosed. Also disclosed are methods of treating hypertension using compounds of Formula 1.0 wherein R is selected from the group consisting of H, halogen and --C(O)OR.sup.6 ; and R.sup.1 is selected from the group consisting of --OR.sup.14, --O(CH.sub.2).sub.a C(H).sub.3-i Z.sub.i and --O(CH.sub.2).sub.h N(R.sup.15).sub.2.

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Patent Owner(s)

  • SCHERING CORPORATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Afonso, Adriano West Caldwell, NJ 42 593
Gentles, Margaret J Bloomfield, NJ 6 197
Weinstein, Jay Upper Montclair, NJ 24 379

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