Drug delivery collagen-impregnated synthetic vascular graft
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United States of America Patent
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Mar 30, 1993
Issued Date -
N/A
app pub date -
Apr 30, 1992
filing date -
Jan 30, 1984
priority date (Note) -
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Abstract
A collagen impregnated vascular graft including drug materials complexed with the collagen to be released slowly from the graft following implant. The graft is a porous synthetic vascular graft substrate having collagen fixed to the graft substrate and cross-linking the collagen in situ to render the porous substrate blood-tight. The drug materials complexed with the collagen fibrils may include antithrombic agents, antibacterial, antimicrobial agents, antifungal agents and the like.
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