LDLR genetic markers associated with age of onset of Alzheimer's Disease
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United States of America Patent
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Issued Date -
Jul 13, 2006
app pub date -
Jan 14, 2005
filing date -
Jan 22, 2004
priority date (Note) -
Abandoned
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Abstract
Haplotypes in the LDLR gene associated: with age of onset of Alzheimer's Disease are disclosed. Compositions and methods for detecting and using these LDLR haplotypes in a variety of clinical applications are disclosed. Such applications include articles of manufacture comprising compounds effective in delaying the age of onset of AD in individuals at risk for developing AD and having one of these LDLR haplotypes, methods and kits for predicting the age of onset of AD in an individual at risk for developing AD based upon his/her haplotype profile, and methods for delaying the age of onset of AD in individuals at risk for developing AD based upon their haplotype profile.
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