Nucleic acid agents for downregulating H19 and methods of using same

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United States of America Patent

PATENT NO 8067573
APP PUB NO 20090143321A1
SERIAL NO

11994810

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides isolated oligonucleotides capable of down-regulating a level of H19 mRNA in cancer cells. Articles of manufacture comprising agents capable of downregulating H19 mRNA in combination with an additional anti-cancer treatment are disclosed as well as methods of treating cancer by administering same.

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Patent Owner(s)

  • YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hochberg, Avraham Jerusalem, IL 5 24
Matouk, Imad East Jerusalem, IL 2 14

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