Combination therapy intravaginal rings
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United States of America Patent
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Nov 27, 2018
Grant Date -
May 21, 2015
app pub date -
Nov 13, 2014
filing date -
Nov 14, 2013
priority date (Note) -
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Abstract
The present invention provides improved intravaginal drug delivery devices, i.e., intravaginal rings, useful for the prophylactic administration of dapivirine in combination with either an antimicrobial compound or a contraceptive to a human. The present invention also provides methods of blocking DNA polymerization by an HIV reverse transcriptase enzyme, methods of preventing HIV infection in a female human, methods of treating HIV infection in a female human, methods of preventing unintended pregnancy in a female human, and methods of preparing intravaginal rings.
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