COMPOSITIONS AND METHODS FOR ASSESSING AND TREATING T CELL DYSFUNCTION

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United States of America Patent

APP PUB NO 20240148791A1
SERIAL NO

18549252

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present disclosure provides modified immune cells or precursors thereof (e.g., gene edited modified T cells) comprising a modification in an endogenous gene locus encoding SOX and/or ID3. Methods for assessing and treating T cell dysfunction are also provided.

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Patent Owner(s)

Patent OwnerAddress
UNIV PENNSYLVANIAPENN CENTER FOR INMOVATION 3160 CHESTNUT STREET SUITE 200 PHILADELPHIA PENNSYLVANIA 19104 UNITED STATES OF AMERICA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Berger, Shelley L Wayne, US 6 8
Gomez, M Angela Aznar Philadelphia, US 1 0
Good, Charly R Springfield, US 1 0
June, Carl H Merion Station, US 195 6891
Kuramitsu, Shunichiro Nagoya, JP 1 0
Young, Regina M Bryn Mawr, US 7 47

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