Lubricious antithrombogenic catheters, guidewires and coatings
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United States of America Patent
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-
Aug 4, 1992
Grant Date -
N/A
app pub date -
Dec 15, 1989
filing date -
Dec 15, 1989
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
Method for rendering a preformed article lubricious and antithrombogenic and a device being the same. On the surface of the article a thin coating of a biologically compatible, lubricious, hydrophilic polymer including acid groups, is provided. On the coating, ammonium cation, and heparin are applied in the manner that heparin is bound by electrostatic attraction to the ammonium cation of the coating to permit time release of heparin. A buffer solution may be applied in a manner to act to enhance the lubriciousness of the coating.
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