US Patent No: 5,965,163
Number of patents in Portfolio can not be more than 2000
Substained release compositions and a method of preparing pharmaceutical compositions
Stats
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Oct 12, 1999
Issued date -
Sep 30, 1997
filing date -
08/944,106
serial no -
In Force
status
Importance
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Abstract
A process for the manufacture of particles comprises mechanically working a mixture of a drug and a hydrophobic and/or hydrophilic fusible carrier in a high speed mixture so as to form agglomerates, breaking the agglomerates to give controlled release particles and optionally continuing the mechanical working with the optional addition of a low percentage of the carrier or diluent.
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First Claim
Related Publications
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International Classification(s)
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- [Patents Count]
Cited Art
| Patent Info | (Count) | # Cites | Year |
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| 4,828,836 Controlled release pharmaceutical composition | 127 | 1987 | |
| 4,834,985 Controlled release pharmaceutical composition | 160 | 1987 | |
| 4,990,341 Controlled release hydromorphone composition | 83 | 1989 | |
| 5,266,331 Controlled release oxycodone compositions | 91 | 1991 | |
| 5,273,760 Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer | 123 | 1991 | |
| 5,286,493 Stabilized controlled release formulations having acrylic polymer coating | 124 | 1992 | |
| 5,549,912 Controlled release oxycodone compositions | 79 | 1993 | |
| 5,580,578 Controlled release formulations coated with aqueous dispersions of acrylic polymers | 96 | 1993 | |
| 5,639,476 Controlled release formulations coated with aqueous dispersions of acrylic polymers | 233 | 1995 | |
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| 4,844,907 Pharmaceutical composition comprising analgesic and anti-inflammatory agent | 97 | 1986 | |
| 5,500,227 Immediate release tablet cores of insoluble drugs having sustained-release coating | 92 | 1993 | |
| 5,849,240 Method of preparing sustained release pharmaceutical compositions | 58 | 1996 | |
| 5,843,480 Controlled release diamorphine formulation | 41 | 1996 | |
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| 5,202,128 Sustained release pharmaceutical composition | 111 | 1990 | |
| 5,330,766 Sustained release pharmaceutical composition | 74 | 1993 | |
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| 4,801,460 Preparation of solid pharmaceutical forms | 109 | 1987 | |
| 5,073,379 Continuous preparation of solid pharmaceutical forms | 79 | 1989 | |
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| 4,967,486 Microwave assisted fluidized bed processor | 32 | 1989 | |
| 5,132,142 Apparatus and method for producing pellets by layering power onto particles | 44 | 1991 | |
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| 4,861,598 Controlled release bases for pharmaceuticals | 95 | 1986 | |
| 4,970,075 Controlled release bases for pharmaceuticals | 74 | 1989 | |
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| 5,453,283 Orally administered solvent-free pharmaceutical preparation with delayed active-substance release, and a method of preparing the preparation | 20 | 1993 | |
| 5,472,710 Pharmaceutical preparation to be administered orally with controlled release of active substance and method for its manufacture | 43 | 1994 | |
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| 4,483,847 Process for the manufacture of a pharmaceutical composition with a retarded liberation of active material | 62 | 1983 | |
| 5,167,964 Semi-enteric drug delivery systems and methods for preparing same | 65 | 1992 | |
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| 4,343,789 Sustained release pharmaceutical composition of solid medical material | 72 | 1980 | |
| 4,380,534 Solid drug preparations | 40 | 1981 | |
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| 4,613,619 Anti-arrhythmic amino-alcohols | 19 | 1985 | |
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| 5,300,300 Controlled release gastroresistant pharmaceutical formulations for oral administration containing bile acids and their salts | 28 | 1992 | |
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| 4,894,234 Novel drug delivery system for antiarrhythmics | 65 | 1988 | |
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| 4,310,483 Thermal tumbling granulation | 34 | 1979 | |
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| 5,007,790 Sustained-release oral drug dosage form | 130 | 1989 | |
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| 5,133,974 Extended release pharmaceutical formulations | 197 | 1990 | |
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| 5,169,645 Directly compressible granules having improved flow properties | 80 | 1989 | |
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| 4,917,899 Controlled absorption diltiazem formulation | 52 | 1987 | |
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| 4,880,830 Slow release formulation | 45 | 1987 | |
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| 4,844,909 Controlled release hydromorphone composition | 77 | 1987 | |
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| 5,196,203 Theophylline dosage form | 37 | 1991 | |
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| 4,389,393 Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose | 206 | 1982 | |
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| 5,178,868 Dosage form | 51 | 1991 | |
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| 4,935,246 Process for the coating of granules | 99 | 1988 | |
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| 4,329,794 Ripping attachment for dragline | 28 | 1980 | |
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| 4,421,736 Sustained release diethylpropion compositions | 53 | 1982 | |
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| 4,621,114 Propylene resin composition | 33 | 1984 | |
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| 5,591,452 Controlled release formulation | 50 | 1994 | |
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| 5,030,400 Process and an apparatus for agglomeration of a powdery material | 57 | 1990 | |
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| 5,403,593 Melt granulated compositions for preparing sustained release dosage forms | 28 | 1992 | |
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| 5,395,626 Multilayered controlled release pharmaceutical dosage form | 88 | 1994 | |
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| 5,807,583 Process for the preparation of sustained release pellets | 8 | 1995 | |
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| 4,925,675 Erythromycin microencapsulated granules | 28 | 1988 | |
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| 4,834,984 Controlled release dihydrocodeine composition | 73 | 1987 | |
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| 5,271,934 Encapsulated antiperspirant salts and deodorant/antiperspirants | 75 | 1992 | |
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| 4,533,562 Method of preparing coated solid preparations | 47 | 1984 | |
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| 5,204,119 External preparation comprising calcium silicate | 33 | 1991 | |
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| 5,162,117 Controlled release flutamide composition | 50 | 1991 | |
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| 5,023,089 Sustained-release preparations and the process thereof | 44 | 1989 | |
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| 5,292,461 Process for the production of pellets | 46 | 1991 | |
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| 5,443,846 Granulated preparations and method of producing the same | 19 | 1994 | |
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| 5,026,560 Spherical granules having core and their production | 96 | 1988 | |
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| 5,126,145 Controlled release tablet containing water soluble medicament | 96 | 1990 | |
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| 4,801,458 Sustained release pharmaceutical plaster | 89 | 1987 | |
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| 4,987,136 Method for controlling gastrointestinal dysmotility | 80 | 1986 | |
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| 4,366,172 4-Amino-cyclohexanols, their pharmaceutical compositions and methods of use | 28 | 1977 | |
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| 4,259,314 Method and composition for the preparation of controlled long-acting pharmaceuticals | 107 | 1979 | |