Tissue engineered tendons and ligaments
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United States of America Patent
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Jan 11, 2005
Issued Date -
N/A
app pub date -
Sep 25, 2000
filing date -
May 1, 1995
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Connective tissue, including neo-tendons and ligaments, has been constructed using biodegradable synthetic scaffolds seeded with tenocytes. The scaffolds are preferably formed from biodegradable fibers formed of a polymer such as polyglycolic acid-polylactic acid copolymers, and seeded with cells isolated from autologous tendon or ligament by means of enzymatic digestion or direct seeding into tissue culture dishes from explants. The cell polymer constructs are then surgically transplanted to replace missing segments of functioning tendon or ligament.
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