Hybrid random bead/chip based microarray
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United States of America Patent
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Jan 16, 2007
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app pub date -
Jan 22, 2004
filing date -
Jan 22, 2003
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Abstract
A method and apparatus f or performing an assay process, featuring providing microbeads in a solution; placing the microbeads on an alignment substrate; reading codes of the microbeads and the position thereof on the alignment substrate; reading the fluorescence on each microbead and the position order thereof on the alignment substrate; and determining an assay result based on bead position order and bead code of the earlier reading steps, where the microbead is an encoded particle having a particle substrate; a portion of the substrate being made of a substantially single material and having at least one diffraction grating embedded therein, the grating having a resultant refractive index variation within the single material at a grating location; and the grating providing an optical output signal indicative of a code when illuminated by an incident light signal propagating from outside said substrate, the optical output signal being a result of passive, non-resonant scattering from said grating when illuminated by said incident light signal.
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- 15 United States
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Patent Owner(s)
- ILLUMINA, INC.
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Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
---|---|---|---|
Kersey, Alan D | South Glastonbury, CT | 186 | 4644 |
Li, Tuo | East Lyme, CT | 29 | 659 |
Moon, John | Wallingford, CT | 41 | 583 |
Putnam, Martin A | Cheshire, CT | 111 | 3034 |
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Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |
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