Compositions useful as inhibitors of protein kinases

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United States of America Patent

PATENT NO 7652135
APP PUB NO 20050101594A1
SERIAL NO

10949714

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides compounds of formula I:are as described in the specification. These compounds are inhibitors of protein kinase, particularly inhibitors of AKT or PDK1 kinase, mammalian protein kinases involved in proliferative and neurodegenerative disorders. The invention also provides pharmaceutical compositions comprising the compounds of the invention, processes for preparing the compounds, and methods of utilizing those compositions in the treatment of various disorders.

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Patent Owner(s)

  • VERTEX PHARMACEUTICALS INCORPORATED

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Binch, Hayley Encinitas, GB 75 4517
Everitt, Simon Oxfordshire, GB 33 1177
Mazzei, Francesca Wallingford, GB 7 276
Robinson, Daniel Abingdon, GB 46 1003

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