Cyclohexane derivatives and their use as therapeutic agents
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United States of America Patent
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Sep 12, 2006
Grant Date -
Dec 25, 2003
app pub date -
May 16, 2001
filing date -
May 19, 2000
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention relates compounds of formula (I), wherein ring A is a phenyl or pyridyl ring; X represents a linker selected from the group consisting of formulae: (a), (b), (c), (d), and (e); and R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.13, R.sup.14, R.sup.15, R.sup.16, R.sup.17, R.sup.21a and R.sup.21b are as defined herein. The compounds are of particular use in the treatment or prevention of depression, anxiety, pain, inflammation, migraine, emesis or postherpetic neuralgia. ##STR00001##
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