Combination therapy involving diaryl macrocyclic compounds

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United States of America Patent

PATENT NO 11666574
APP PUB NO 20210154198A1
SERIAL NO

17104739

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Abstract

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The present disclosure relates to methods and compositions for treating cancer with a diaryl macrocycle in combination with an inhibitor of MAPK/ERK kinase-1 and -2 (MEK1 and MEK2; MAP2K1 and MAP2K2), such as trametinib.

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Patent Owner(s)

  • TURNING POINT THERAPEUTICS, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cui, Jingrong J San Diego, US 19 64
Deng, Wei San Diego, US 170 1507
Lee, Nathan V San Diego, US 2 1
Murray, Brion W San Diego, US 13 50
Rodon, Laura San Diego, US 4 1
Zhai, Dayong San Diego, US 30 110

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