Amino-5-(5-membered)hetero-arylimidazolone compounds and the use thereof for β-secretase modulation

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United States of America Patent

PATENT NO 7705030
APP PUB NO 20080306091A1
SERIAL NO

12180795

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Abstract

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The present invention provides a 2-amino-5-heteroaryl-5-phenylimidazolone compound of formula IThe present invention also provides methods for the use thereof to inhibit β-secretase (BACE) and treat β-amyloid deposits and neurofibrillary tangles.

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Patent Owner(s)

  • WYETH LLC

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Andrae, Patrick Michael Jamesburg, US 8 158
Erdei, James Joseph Philadelphia, US 12 264
Fobare, William Floyd Lawrenceville, US 12 242
Gunawan, Iwan Suwandi Somerset, US 6 158
Malamas, Michael Sotirios Jamison, US 24 398
Quagliato, Dominick Anthony Bridgewater, US 13 287
Solvibile, William Ronald East Windsor, US 10 116
Yan, Yinfa Bedminister, US 18 371
Zhou, Ping Plainsboro, US 215 1639

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