Sol-gel encapsulated enzyme

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United States of America Patent

PATENT NO 5200334
SERIAL NO

07744524

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Abstract

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An active biological material encapsulated in a glass is formed using a sol-gel process. A metal alkoxide is mixed with water and exposed to ultrasonic energy at a pH.ltoreq.2 to form a single phase solution which is then buffered to a pH between about 5 and 7. The buffered solution is then mixed with the active biological material and the resultant gel is aged and dried. The dried product is a transparent porous glass with substantially all of the added active biological material encapsulated therein, the biological material retaining a high level of activity.

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Patent Owner(s)

  • REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dunn, Bruce S Los Angeles, CA 24 208
Ellerby, Lisa Los Angeles, CA 4 82
Nishida, Clinton Los Angeles, CA 1 67
Nishida, Fumito Los Angeles, CA 13 106
Valentine, Joan S Encino, CA 2 80
Yamanaka, Stacey A Los Angeles, CA 7 429
Zink, Jeffrey I Sherman Oaks, CA 18 246

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